On “Reaching Out,” Queen and Paul Rodgers sing “Lately I’ve been hard to reach / I’ve been too long on my own / everybody has a private world where they can be alone.” These lyrics were sampled on the intro to Eminem’s 2009 single ”Beautiful,” a raw tale of the rapper’s struggles with depression. Half of the song was written while Eminem was in rehab, including lyrics like “I’m just so f—king depressed/I just can’t seem to get out this slump.”

The lyrics pierced the core of Eminem’s audience, who were able to see the parallels between the struggles of a rap superstar and their own issues. The song reached the Top 20 of the Billboard Hot 100 and was nominated for a Best Rap Solo Performance GRAMMY Award. In an interview with MTV about the song, Eminem said it was an important outlet for him at a challenging time.

But it was far from the first time Eminem has discussed mental health. One of the earliest examples was in his song “Stan,” where Eminem rapped from the perspective of an obsessed fan who ended up killing himself and his wife after Eminem failed to respond to his fan mail. In a 2000 interview, Eminem told MTV that he wrote the song to warn fans not to take his lyrics literally